EVENT DESCRIPTION
Intrinsically disordered proteins (IDPs) are abundant components of eukaryotic proteomes and are centrally involved in disease mechanisms, ranging from pathogenic to host proteins. This workshop will cover basic and advanced aspects of how IDPs contribute to disease mechanisms through five training bootcamp sessions to be held in a virtual format, and one in-person event to be held in person at UNSAM University. A dedicated career development roundtable will cover different aspects of career advancement in bioinformatic and biological research.
EVENT REGISTRATION
Participation requires registration but the event is free (no registration fee). Training Bootcamps will be held by Zoom and participation in the training sessions requires each participant to have a personal computer. Participants should have a basic knowledge on protein function and structure. Programing skills are not required but are a plus.
Please register here
LANGUAGE
- English
DAYS
Virtual Bootcamp Training
- Monday 23/5. 9 AM to 6 PM
- Tuesday 24/5. 9 AM to 1 PM
- Thursday 26/5. 9 AM to 6 PM
In person Symposium
- Tuesday 24/5. 2 to 6 PM.
SUMMARY SCHEDULE
Monday May 23rd
- Prediction and analysis of functional motifs mediating viral and bacterial pathogen hijack. - Lucia Chemes and Juliana Glavina
- Disease associated variants in liquid-liquid phase separation proteins. DisPhaseDB: An integrative database. - Cristina Marino Buslje and Alvaro M Navarro.
Tuesday May 24rd
- Structural constraints on evolutionary rates of IDPs. - Nicolás Palopoli and Gustavo Parisi.
- SYMPOSIUM IN PERSON (IIB-UNSAM) - IDPs and Disease Mechanisms. Chair: Lucía Chemes.
- Disease-associated variants in liquid-liquid phase separation - Cristina Marino Buslje (Leloir Institute, Argentina)
- Targeting liquid-liquid phase separation in disease - Peter Tompa (VUB-Brussels, Belgium)
- Pathogen hijack of short linear motifs - Toby Gibson (EMBL Heidelberg, Germany)
- Why do amyloidogenic proteins evolve faster? - Gustavo Parisi (UNQ, Buenos Aires, Argentina)
- CAREER DEVELOPMENT ROUNDTABLE - Career paths in bioinformatic and scientific research
- Senior PIs: P. Tompa, T. Gibson, S. Fornasari
- Junior Scientists: N. Palopoli, J. Iserte, E. Martinez-Perez
- Students/Trainees: Matyas Pakjos
Thursday May 26th
- Exploring protein disorder and diseases with MobiDB and DisProt databases - Alex Monzón and Federica Quaglia.
- Functional modules in human pathogenic proteins assessed through database (PED and ELM) analysis and predictions (Anchor and AlphaFold) - Peter Tompa and Tamas Lazar.
Friday May 27th
- SUPERVISORY BOARD MEETING - Exclusive for IDPFun Supervisory Board Members.